The workshop brings together leaders in the development of algorithms, applications, frameworks, and libraries for addressing data-intensive problems at unprecedented scale. Examples of topics that this symposium explore include new kinds of applications that focus on analytics and informatics, integration of machine learning algorithms with analysis of multimodal data, ways to express workflows that couple tasks in data-intensive analysis, and component models for productively building data-intensive applications. The workshop was held during April 14-15, 2011.